Alcat Scientific Dossier
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Understanding Your Results
Innate Immune Activity Conditions the Effect of Regulatory Variants upon Monocyte Gene Expression
Discussion: Interindividual variation in immune responses is accompanied by diverging patterns of gene regulation dependent on underlying genotype.
Benjamin P. Fairfax,* Peter Humburg, Seiko Makino, Vivek Naranbhai, Daniel Wong, Evelyn Lau, Luke Jostins, Katharine Plant, Robert Andrews, Chris McGee, Julian C. Knight*
Many genetic variants associated with common disease susceptibility occur close to immune- related genes in noncoding DNA, suggestive of a regulatory function.
Chronic inflammation as a determinant of future aging phenotypes.
Interpretation: Chronic inflammation, as ascertained by repeat measurements, was associated with a range of unhealthy aging phenotypes and a decreased likelihood of successful aging.
Tasnime N. Akbaraly PhD, Mark Hamer PhD, Jane E. Ferrie PhD, Gordon Lowe DSc, G. David Batty PhD,Gareth Hagger-Johnson PhD, Archana Singh-Manoux PhD, Martin J. Shipley MSc, Mika Kivimäki PhD.
The importance of chronic inflammation as a determinant of aging phenotypes may have been underestimated in previous studies that used a single measurement of inflammatory markers.
New biometric tests invade the NBA
In the field of nutritional analysis, the payoff for a blood draw comes when a company such as Cell Science Systems -- in attendance at the NBSCA vendor show -- generates a one-page, color-coded report that indicates whether a player has any debilitating food allergies or sensitivities to any of 100 specific foods. A universe of dining threats is identified.
Spectrum of gluten-related disorders: consensus on new nomenclature and classification.
Conclusions: It is now becoming apparent that reactions to gluten are not limited to CD, rather we now appreciate the existence of a spectrum of gluten-related disorders.
Anna Sapone1,2, Julio C Bai3, Carolina Ciacci4, Jernej Dolinsek5, Peter HR Green6, Marios Hadjivassiliou7,Katri Kaukinen8, Kamran Rostami9, David S Sanders10, Michael Schumann11, Reiner Ullrich11, Danilo Villalta 12,Umberto Volta13, Carlo Catassi1,14 and Alessio Fasano1*
A decade ago celiac disease was considered extremely rare outside Europe and, therefore, was almost completely ignored by health care professionals. In only 10 years, key milestones have moved celiac disease from obscurity into the popular spotlight worldwide. Now we are observing another interesting phenomenon that is generating great confusion among health care professionals.
Food reactivity on the ALCAT leukocyte activation test is associated with up-regulation of CD11b on T cells
Hypothesis: We hypothesized that positivity on the ALCAT test is associated with up-regulation of plasma membrane markers on peripheral blood immune cells.
Ayaz Ghani md 1, Wajahat Mehal md dphil 1, Ather Ali nd mph 2
Severe intolerance on the ALCAT test is associated with an up-regulation of CD11b on CD4+ and CD8+ T cells.
ALCAT | Available for over 25 years
The Alcat Test is a lab based immune stimulation test in which a patient's WBC's are challenged with various substances including foods, additives, colorings, chemicals, medicinal herbs, functional foods, molds and pharmaceutical compounds. The patient's unique set of responses help to identify substances that may trigger potentially harmful immune system reactions.
The Alcat Test objectively classifies a patient's response to each test substance as reactive, borderline or non-reactive. Based on these classifications, a cus-tomized elimination/rotation diet may be designed to effectively eliminate the specific triggers of chronic immune system activation. By reducing this ongoing burden - and in particular, by reversing the sustained and destructive inflammation it produces - normal body functions and immune system balance can be improved.
The Gut Health Profile (GHP) is the latest and most comprehensive way to learn about your body's reaction to gluten. Celiac disease affects 1 in 133 people, and of those, approximately 95% are undiagnosed! Read More
In our ongoing efforts to offer valuable diagnostic testing to our providers, Cell Science Systems is presenting new specialized assays that expand the boundaries of critical knowledge needed to improve the health of your patients. These assays includes Telomere Length Test, MTHFR Genetic Mutation, Vitamin D and Adrenal Stress Profile. Read More